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This is a pretty tricky fight; definitely the hardest one in the raid. I encourage you to watch FatBoss’s guide for it since most of the difficulties come from the generic mechanics and not Windwalker specific stuff.
In general, you want to prioritize killing Corrupted Wisp > Nightmare Ancient > Twisted Sister > Rotten Drake. On Mythic, you’ll want to prioritize Twisted Sister higher and most likely ignore Rotten Drake.
Be careful with Dread Thorns damage. You can quickly get hit badly by it if you Touch of Death ahead of Dread Thorns and get 1.5 million damage reflected onto you. Even Touch of Karma isn’t very safe against Dread Thorns.
Focus on dodging Nightmare Brambles and moving out of Scorned Touch. You can easily hit Twisted Sister from a pretty huge range so I wouldn’t be too scared of staying away from melee while killing it. Tiger’s Lust DOES NOT remove Nightmare Brambles root which is a shame. Flying Serpent Kick removes Nightmare Brambles from the ground without taking any damage, so use this to clear in a line whenever required. Clearing every 25 seconds at no cost is very good, you won’t clear as much as a rogue/hunter each time but overall it helps a lot.
A lot of things change here on mythic. As we write this, guilds progressing on Cenarius don’t have the gear/damage to be able to both kill Rotten Drake and push Cenarius to 35% in time. Therefore we’ll assume you’re ignoring Rotten Drake.
0:00 Blow all cooldowns on Cenarius, don’t wait for Nightmare Ancient to spawn.
0:30 Around this timer you should have Nightmare Ancient up. You don’t necessarily want to delay Strike of the Windlord until you get to him since that would probably just mean the next strike is up after Nightmare Ancient dies and you won’t have it up on first Twisted Sister.
1:35 you should be leaving boss, keep Serenity and use it as soon as possible on Twisted Sister; you can use Touch of Death as it comes up if this prevents your group getting another cast of Scorned Touch, otherwise you can keep it for 3 minutes in (double Twisted Sister wave). If your group’s dps on laughing Twisted Sister is good, you will not have time for Touch of Death to hit her before she dies.
3:10 Around this timer you should try to do your best destroying Twisted Sister. Focus one down but fit in Spinning Crane Kick during your Serenity and tag both with Spinning Crane Kick. Spinning Crane Kick is more efficient than Blackout Kick single target with two stacks and cleaving second Twisted Sister down will help immensely. Touch of Death the priority Twisted Sister if you have kept it.
Legendary gloves are VERY good in this fight. If you have them, I’d use first Touch of Death on Cenarius+Nightmare Ancient(use Diffuse Magic for Dread Thorns) and delay second for the double Twisted Sister.
We cannot stress enough how strong Flying Serpent Kick is on this fight.
This is actually the easiest fight to get full benefit from Touch of Karma. However, be careful; soaking a full Touch of Karma will leave you taking a dot for 25% of your health from Dread Thorns, on top of whatever damage you deal during this DoT. It can quickly be very dangerous!